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N-press has nebivolol that is a highly selective Beta1 receptor blocker. It gives additional vasodilator and antioxidant properties. Its BP-lowering effect is linked to a reduction in peripheral vascular resistance (PVR). This medicine has a nitric-oxide (NO) potentiating, vasodilator effect. N-press-5 is recommended for use in patients with type2 diabetes mellitus concurrent with arterial hypertension.